Skip to content

Jarrow Formulas Methyl Folate vs Active Iron Active Folic

Side-by-side comparison of scores, ingredients, prices and real customer feedback for Jarrow Formulas Methyl Folate and Active Iron Active Folic.

Last verified: 28 Mar 2026 · Based on 54 reviews

81.0
Score Summary

Jarrow Formulas Methyl Folate scores 81.0/100 vs Active Iron Active Folic at 80.0/100. Jarrow Formulas Methyl Folate wins on effectiveness, ingredient quality. Active Iron Active Folic is stronger on side effects and certifications.

Jarrow Formulas Methyl Folate vs Active Iron Active Folic: What Does the Data Say?

Vegan Methyl Folate from Jarrow Formulas edges out Active Folic with an overall score of 81.0/100 against 80.0/100. Both deliver 400 mcg of Quatrefolic methylfolate yet the Jarrow version scores higher on effectiveness at 85.0/100 and ingredient quality at 90.0/100 while value sits tied at 80.0/100 for each. Vegan Methyl Folate comes in veggie capsules that reviewers call small and easy to swallow with no taste or smell. Active Folic uses standard capsules that also swallow easily but lacks the vegan certification.

People with MTHFR gene variants who cannot convert synthetic folic acid should pick Vegan Methyl Folate because it bypasses those conversion problems and delivers clear energy and mood lifts after a few weeks. Those who need something gentle on the stomach and follow UK preconception guidelines might prefer Active Folic for its consistent GI tolerability. Budget buyers will favour the Jarrow product at £9.70 over the £12.99 Active Iron option. Anyone sensitive to anxiety or agitation from methylfolate alone should consider pairing Vegan Methyl Folate with B12 and B6 or switch to folinic acid instead.

Practical matters matter too. Vegan Methyl Folate suits users who want a fully plant-based capsule and report no smell. Active Folic works for those who dislike any hint of animal ingredients in processing yet still need the methylfolate form. Both capsules stay small enough for daily use without fuss.

How Do the Scores Compare?

Vegan Methyl Folate, 400 mc...
Active Folic 60 Capsules
Vegan Methyl Folate, 400 mcg, 60 Veggie Capsules
Vegan Methyl Folate, 400 mc...
Jarrow Formulas
Active Folic 60 Capsules
Active Folic 60 Capsules
Active Iron
Overall Score 81.0 80.0
Effectiveness 85.0/100
Best
80.0/100
Ingredient Quality 90.0/100
Best
80.0/100
Value for Money 80.0/100
Best
80.0/100
Best
Side Effects 77.0/100 90.0/100
Best
Certifications 35.0/100 40.0/100
Best
Best Price £9.89 iHerb →
Cheapest
£12.99 Holland & Barrett →
Form None capsule
Dose None None
Third-Party Tested ✗ No ✗ No
Reviews Analysed 50 4

Vegan Methyl Folate, 400 mcg, 60...

Pros

  • Quatrefolic® (6S)-5-MTHF bypasses MTHFR conversion issues — multiple reviewers specifically chose it for this reason
  • Small capsule size consistently praised; neutral taste, no smell
  • Energy boost and mood improvement reported by reviewers after a few weeks of regular use
  • Clean excipient list — vegetable-source magnesium stearate, HPMC capsule, no unnecessary fillers

Cons

  • Can cause anxiety or agitation in sensitive individuals — one reviewer switched to folinic acid specifically because of this
  • Works best paired with B12 and B6; some reviewers noted irritability when taken without a B-complex
  • Not universally appropriate — one reviewer's doctor advised against the methyl form due to transulfation pathway issues
  • No verified third-party testing per product specs

Best For

People with MTHFR gene variants who cannot efficiently convert synthetic folic acid Women planning pregnancy or in the first trimester needing bioavailable B9 Those with confirmed folate deficiency prescribed methylfolate by a doctor People with thalassemia or related anaemia where iron supplementation is not suitable
View full review →

Active Folic 60 Capsules

Pros

  • Methylfolate form (Quatrefolic®) offers superior bioavailability compared to synthetic folic acid
  • 400μg dose meets UK and international preconception/pregnancy supplementation guidelines
  • Consistently praised by reviewers for gentle GI tolerability and ease of swallowing
  • Established brand (Active Iron) with positive reputation for quality supplements

Cons

  • No third-party testing certification mentioned (USP, NSF, etc.)
  • Not vegan (capsule and processing may contain animal-derived ingredients)
  • Only 4 reviews available—limited user feedback pool
  • No clinical data provided comparing actual absorption rates to standard folic acid claims

Best For

Women planning pregnancy or in early pregnancy Those with MTHFR gene variations who may benefit from methylfolate People seeking bioavailable folate without synthetic folic acid Users sensitive to standard supplements with good GI tolerance
View full review →

Score Breakdown: Jarrow Formulas Methyl Folate vs Active Iron Active Folic

Jarrow Formulas Methyl Folate Winner 81.0/100

Jarrow's 400 mcg methylfolate uses Quatrefolic® — the glucosamine salt of (6S)-5-MTHF — which the body absorbs without the conversion step that folic acid requires.

Effectiveness
Vegan Methyl Fol..
85.0/100
Active Folic 60 ..
80.0/100
Ingredient Quality
Vegan Methyl Fol..
90.0/100
Active Folic 60 ..
80.0/100
Value for Money
Vegan Methyl Fol..
80.0/100
Active Folic 60 ..
80.0/100
Side Effects
Vegan Methyl Fol..
77.0/100
Active Folic 60 ..
90.0/100
Certifications
Vegan Methyl Fol..
35.0/100
Active Folic 60 ..
40.0/100

What are the key differences?

Jarrow Formulas Methyl Folate is best for: People with MTHFR gene variants who cannot efficiently convert synthetic folic acid, Women planning pregnancy or in the first trimester needing bioavailable B9
Active Iron Active Folic is best for: Women planning pregnancy or in early pregnancy, Those with MTHFR gene variations who may benefit from methylfolate

Frequently Asked Questions

Which is better, Jarrow Formulas Methyl Folate or Active Iron Active Folic?
Jarrow Formulas Methyl Folate scores 81.0/100 overall while Active Iron Active Folic scores 80.0/100. Jarrow Formulas Methyl Folate comes out ahead, scoring higher on effectiveness (85.0 vs 80.0). Jarrow Formulas Methyl Folate is best suited for People with MTHFR gene variants who cannot efficiently convert synthetic folic acid and Women planning pregnancy or in the first trimester needing bioavailable B9. Active Iron Active Folic is better for Women planning pregnancy or in early pregnancy and Those with MTHFR gene variations who may benefit from methylfolate.
Is Jarrow Formulas Methyl Folate worth the price compared to Active Iron Active Folic?
Jarrow Formulas Methyl Folate costs £9.89 while Active Iron Active Folic is £12.99. For value, Jarrow Formulas Methyl Folate scores 80.0/100 vs Active Iron Active Folic's 80.0/100. Both offer similar value for money.
Which has fewer side effects?
Jarrow Formulas Methyl Folate scores 77.0/100 for side effects (higher means fewer reported issues) while Active Iron Active Folic scores 90.0/100. Reviewers report fewer side effects with Active Iron Active Folic. For certification and testing, Jarrow Formulas Methyl Folate scores 35.0/100 vs Active Iron Active Folic's 40.0/100. Always consult a healthcare professional before starting any supplement.

Related Product Comparisons

Disclaimer: AIScored provides data-driven comparisons based on publicly available reviews. This is not medical advice. Affiliate links may earn us a commission at no extra cost to you.

Feedback & Suggestions

Spotted an issue? Wrong price, incorrect data, or something else off? Let us know and we'll fix it.

Missing a product you'd like us to review? Tell us the product name and we'll consider adding it.