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Solgar Folate Metafolin 1000µg vs Active Iron Active Folic

Side-by-side comparison of scores, ingredients, prices and real customer feedback for Solgar Folate Metafolin 1000µg and Active Iron Active Folic.

Last verified: 01 Mar 2026 · Based on 61 reviews

Our Verdict: Solgar Folate Metafolin 1000µg or Active Iron Active Folic?

Solgar Folate (As Metafolin) 1000µg 60 Tablets wins. Its 86.0/100 score comes from a 1000µg dose shown to raise blood levels for people with MTHFR gene mutations. Pick Active Iron Active Folic 60 Capsules for a cheaper £12.99 option for women planning pregnancy.

— AIScored Editorial Team

86.0
Score Summary

Solgar Folate Metafolin 1000µg scores 86.0/100 vs Active Iron Active Folic at 80.0/100. Solgar Folate Metafolin 1000µg wins on effectiveness, ingredient quality, side effects. Active Iron Active Folic is stronger on value for money.

Solgar Folate Metafolin 1000µg vs Active Iron Active Folic: What Does the Data Say?

Folate (As Metafolin) 1000µg 60 Tablets uses the bioactive Metafolin L-methylfolate form that gets absorbed directly. Active Folic 60 Capsules relies on the Quatrefolic methylfolate version instead. The first product delivers 1000µg per tablet while the second sticks to a 400µg dose in capsule form. Solgar scores 86.0/100 overall with 88.0/100 on effectiveness and 93.0/100 on ingredient quality yet only 73.0/100 on value. Active Iron hits 80.0/100 across the board including better value at 80.0/100.

People with confirmed MTHFR gene mutations or diagnosed folate deficiency should pick Folate (As Metafolin) 1000µg 60 Tablets at £16.94. It suits those with elevated homocysteine too thanks to its higher strength and lab confirmed blood level improvements plus reported energy gains. Others planning pregnancy or seeking standard guideline doses on a tighter budget will prefer Active Folic 60 Capsules at £12.99 for its guideline matching amount and gentle tolerability. The capsule wins on value for money while the tablet takes the lead in effectiveness and quality.

Practical matters matter here. Reviewers say the capsule feels easy to swallow with no stomach upset. Tablets lack any taste complaints but the higher dose means medical supervision makes sense before starting. Both come in packs of 60.

How Do the Scores Compare?

Folate (As Metafolin) 1000µ...
Active Folic 60 Capsules
Folate (As Metafolin) 1000µg 60 Tablets
Folate (As Metafolin) 1000µ...
Solgar
Active Folic 60 Capsules
Active Folic 60 Capsules
Active Iron
Overall Score 86.0 80.0
Effectiveness 88.0/100
Best
80.0/100
Ingredient Quality 93.0/100
Best
80.0/100
Value for Money 73.0/100 80.0/100
Best
Side Effects 93.0/100
Best
90.0/100
Certifications 70.0/100
Best
40.0/100
Best Price
£11.91
£9.66 Amazon UK →
-19% deal
£12.99 Holland & Barrett →
Form Tablets capsule
Dose None None
Third-Party Tested ✗ No ✗ No
Reviews Analysed 57 4

Folate (As Metafolin) 1000µg 60 Tablets

Pros

  • Bioactive Metafolin® form (L-methylfolate) absorbed directly without MTHFR conversion — critical for MTHFR gene variant carriers
  • Multiple reviewers confirmed improved blood folate levels via lab tests, not just subjective feeling
  • Widely reported energy improvement and reduction in fatigue after consistent use
  • Clean ingredient profile — certified gluten-free, Kosher Parve, no artificial additives; packaged in glass bottle

Cons

  • Not third-party tested (e.g. NSF, Informed Sport) — relevant for those needing full verification
  • 1000mcg dose significantly exceeds the standard adult RDA (400mcg) and pregnancy recommendation (600mcg) — medical supervision advisable
  • Premium price point relative to standard folic acid alternatives; 60 tablets is a 2-month supply at 1/day
  • Isolated reports of tablets being difficult to swallow for some users

Best For

Women planning pregnancy or in early pregnancy People with confirmed MTHFR gene mutations (C677T, A1298C) Those with diagnosed folate deficiency or elevated homocysteine Anyone who hasn't responded well to standard folic acid supplementation Individuals on methotrexate or other medications that deplete folate People seeking a clean, additive-free premium folate supplement
View full review →

Active Folic 60 Capsules

Pros

  • Methylfolate form (Quatrefolic®) offers superior bioavailability compared to synthetic folic acid
  • 400μg dose meets UK and international preconception/pregnancy supplementation guidelines
  • Consistently praised by reviewers for gentle GI tolerability and ease of swallowing
  • Established brand (Active Iron) with positive reputation for quality supplements

Cons

  • No third-party testing certification mentioned (USP, NSF, etc.)
  • Not vegan (capsule and processing may contain animal-derived ingredients)
  • Only 4 reviews available—limited user feedback pool
  • No clinical data provided comparing actual absorption rates to standard folic acid claims

Best For

Women planning pregnancy or in early pregnancy Those with MTHFR gene variations who may benefit from methylfolate People seeking bioavailable folate without synthetic folic acid Users sensitive to standard supplements with good GI tolerance
View full review →

Score Breakdown: Solgar Folate Metafolin 1000µg vs Active Iron Active Folic

Solgar Folate Metafolin 1000µg Winner 86.0/100

Solgar's Folate as Metafolin 1000mcg delivers L-methylfolate (5-MTHF) via the patented Metafolin® form — the bioidentical, body-ready form of folate that bypasses the MTHFR enzyme conversion required by standard folic acid.

Effectiveness
Folate (As Metaf..
88.0/100
Active Folic 60 ..
80.0/100
Ingredient Quality
Folate (As Metaf..
93.0/100
Active Folic 60 ..
80.0/100
Value for Money
Folate (As Metaf..
73.0/100
Active Folic 60 ..
80.0/100
Side Effects
Folate (As Metaf..
93.0/100
Active Folic 60 ..
90.0/100
Certifications
Folate (As Metaf..
70.0/100
Active Folic 60 ..
40.0/100

What are the key differences?

Solgar Folate Metafolin 1000µg is best for: Women planning pregnancy or in early pregnancy, People with confirmed MTHFR gene mutations (C677T, A1298C)
Active Iron Active Folic is best for: Women planning pregnancy or in early pregnancy, Those with MTHFR gene variations who may benefit from methylfolate

Frequently Asked Questions

Which is better, Solgar Folate Metafolin 1000µg or Active Iron Active Folic?
Solgar Folate (As Metafolin) 1000µg 60 Tablets wins. Its 86.0/100 score comes from a 1000µg dose shown to raise blood levels for people with MTHFR gene mutations. Pick Active Iron Active Folic 60 Capsules for a cheaper £12.99 option for women planning pregnancy. Solgar Folate Metafolin 1000µg scores 86.0/100 overall while Active Iron Active Folic scores 80.0/100. Solgar Folate Metafolin 1000µg comes out ahead, scoring higher on effectiveness (88.0 vs 80.0). Solgar Folate Metafolin 1000µg is best suited for Women planning pregnancy or in early pregnancy and People with confirmed MTHFR gene mutations (C677T, A1298C). Active Iron Active Folic is better for Women planning pregnancy or in early pregnancy and Those with MTHFR gene variations who may benefit from methylfolate.
Is Solgar Folate Metafolin 1000µg worth the price compared to Active Iron Active Folic?
Solgar Folate Metafolin 1000µg costs £9.66 while Active Iron Active Folic is £12.99. For value, Solgar Folate Metafolin 1000µg scores 73.0/100 vs Active Iron Active Folic's 80.0/100. Active Iron Active Folic delivers better value relative to its quality. Note that Solgar Folate Metafolin 1000µg comes as tablets while Active Iron Active Folic is capsule, which may affect your preference.
Which has fewer side effects?
Solgar Folate Metafolin 1000µg scores 93.0/100 for side effects (higher means fewer reported issues) while Active Iron Active Folic scores 90.0/100. Reviewers report fewer side effects with Solgar Folate Metafolin 1000µg. For certification and testing, Solgar Folate Metafolin 1000µg scores 70.0/100 vs Active Iron Active Folic's 40.0/100. Always consult a healthcare professional before starting any supplement.

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Disclaimer: AIScored provides data-driven comparisons based on publicly available reviews. This is not medical advice. Affiliate links may earn us a commission at no extra cost to you.

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